​Molecular basis for activation and biased signalling at the thrombin-activated GPCR Proteinase Activated Receptor-4 (PAR4)
Targeting a PAR4 carboxyl terminal motif to regulate platelet function.
GPCR mediated EGFR transactivation regulates TRPV4 action in the vasculature. 
Neutrophil elastase and proteinase-3 trigger G protein-biased signaling through proteinase-activated receptor-1 (PAR1).
TRPM8 activation attenuates inflammatory responses in mouse models of colitis.
Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2).

Reviews
Proteinases, their extracellular targets, and inflammatory signalling. 
Targeting proteinase-activated receptors: therapeutic potential and challenges
Structure, function and pathophysiology of proteinase activated receptors.